imageThe Scripps Translational Science Institute (STSI) is situated in La Jolla, the heart of one of the nation’s most entrepreneurial and successful academic-industry bioscience hubs. To accelerate the productivity of translational and clinical research, STSI collaborates with many of the area’s biopharmaceutical and other life science companies, wireless technology companies and academic research organizations, all of which are located within 30 miles of the institute. (Source of images: CONNECT’s La Jolla Research & Innovation Summit Report, March 2010.)

The collaboration philosophy at STSI is highly entrepreneurial with a focus on building sustainable relationships that leverage the expertise and resources of the partners in the relationship and to facilitate projects that lead to the mutual benefit of the parties as well as the advancement of translational medicine and science.

STSI is situated in the heart of San Diego’s life sciences cluster, one of the nation’s most entrepreneurial and successful academic-industry bioscience hubs. In addition to research excellence, the San Diego life science community is known for its collaborative spirit and willingness to take risks to bring new medicines and other therapies to patients.

While many of its collaborations are local, STSI and its researchers also collaborate with many commercial enterprises and academic institutions on a national and international basis. Several fellow recipients of the NIH Clinical and Translational Science Award (CTSA) are among STSI’s collaborators.

Relationships with industry and academic organizations benefit STSI by providing additional sources of funding; and access to technologies including those undergoing commercial development and to knowledge/know-how and/or data that support and expand the institute’s overall research activities. Many collaborations include reciprocal access to collections of research samples and trial results and other resources needed for research on the genetics of cardiovascular disease, metabolic diseases, cancer and other diseases.

STSI’s most important relationship is the collaboration that led to its formation. STSI is the research bridge between Scripps Health, recently named by Thompson Reuters as one of the top 10 health care delivery systems in the U.S., and The Scripps Research Institute (TSRI), the world’s largest independent non-profit biomedical research facility. As the bridge between these two organizations, STSI enjoys a tremendous amount of intellectual rapport from both a basic research perspective and, more uniquely, from a comprehensive clinical perspective.

Genomics Research Collaborations

Pacific Biosciences Next gen sequencing
Life Technologies Sample prep for sequencing
Prognosys Biosciences Sequencing tumor
Complete Genomics Next gen sequencing
Illumina Bioinformatics
Raindance Technologies Sample prep for sequencing
Regulus Therapeutics miRNA for CV therapeutics
Gen-Probe Fusion genes in cancer
Agilent Sample prep for sequencing
GeneGo Gene ontogeny/pathways
Sangamo Biosciences Genome editing with engineered zinc finger nucleases

Clinical Research Collaborations

Sanofi-aventis Individualized medicine
Qualcomm Wireless medicine
The Medicines Company Anti-platelet clinical trial
Navigenics, Microsoft & Affymetrix Clinical assessment of genome scans (Scripps Genomic Health Initiative)
HUYA Biosciences Atrial fibrillation drug
Portola Pharmaceuticals Anti-platelet clinical trial using genotyping
Medtronic Prediction of ICD need
CardioDx Prediction of vulnerable plaque
Johnson & Johnson Circulating endothelial cells research
Accumetrics Clinical trial of individualized dosing
WebMD Educating physicians on genomic medicine
GE Healthcare Wireless medicine
Quest Diagnostics Circulating endothelial cells research
Medco Health Wellderly
Molecular Response Molecular markers to predict patient’s response to drug
Biological Dynamics Biomarkers

Collaborations with other Clinical and Translational Science Award (CTSA) institutions

Oregon Health Sciences University Wellderly, genomics of aging & sarcopenia
University of California, San Francisco Wellderly & genomics of osteopenia
University of Utah Genomics of atrial fibrillation
University of Pennsylvania (Children’s Hospital of Pennsylvania) Neuroblastoma
UC San Diego Epigenomics & Alzheimer’s disease
Stanford University