Healthy Aging – Wellderly

In 2007, researchers at Scripps Translational Science Institute launched the Wellderly study in the hopes of unlocking the genetic secrets behind lifelong health. Genetic factors that protect against disease in genetically exceptional individuals have been successfully translated to drugs for the general population. This ongoing study has enrolled more than 1,400 people from across the country ranging in age from 80 to 105, and who have not developed any common chronic medical conditions or diseases.

Initial findings, published in 2016 in the scientific journal Cell, suggest a possible link between long-term cognitive health and protection from chronic diseases, including cancer, heart disease, and diabetes, which account for 90 percent of all deaths in the United States, and more than 75 percent of the health care costs.

Genomic data from this study has been made freely available to the scientific community through STSI’s Variant Browser.

Modern medicine makes it possible to extend a person’s lifespan for years. But simply extending lifespan is not enough, we want to extend healthspan.

Ali Torkamani, PhD

Director, Genome Informatics


Sarah Topol, R.N.
Study Coordinator
[email protected]