Scripps Translational Science Institute

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Research Collaborations

The collaboration philosophy at the Scripps Translational Science Institute (STSI) is highly entrepreneurial with a focus on building sustainable relationships that leverage the expertise and resources of the partners in the relationship and to facilitate projects that lead to the mutual benefit of the parties as well as the advancement of translational medicine and science.

To accelerate the productivity of translational and clinical research, the Scripps Translational Science Institute (STSI) has established research collaborations with other academic research institutions, biopharmaceutical and other life science companies as well as wireless technology companies. Through its collaborations with the wireless technology industry, STSI is working to help realize the potential value of digital medicine to health care.

STSI is situated in the heart of San Diego’s life sciences cluster, one of the nation’s most entrepreneurial and successful academic-industry bioscience hubs. In addition to research excellence, the San Diego life science community is known for its collaborative spirit and willingness to take risks to bring new medicines and other therapies to patients.

While many of its collaborations are local, STSI and its researchers also collaborate with many commercial enterprises and academic institutions on a national or international basis. Several fellow recipients of the NIH Clinical and Translational Science Award (CTSA) are among STSI’s collaborators.

Relationships with industry and academic organizations benefit STSI by providing additional sources of funding; and access to technologies including those undergoing commercial development and to knowledge/know-how and/or data that support and expand the institute’s overall research activities. Many collaborations include reciprocal access to collections of research samples and trial results and other resources needed for research on the genetics of cardiovascular disease, metabolic diseases, cancer and other diseases.

STSI’s most important relationship is the collaboration that led to is formation. STSI is the research bridge between Scripps Health, recently named by Thompson Reuters as one of the top 10 health care delivery systems in the U.S., and The Scripps Research Institute (TSRI), the world’s largest independent non-profit biomedical research facility. As the bridge between these two organizations, STSI enjoys a tremendous amount of intellectual rapport from both a basic research perspective and, more uniquely, from a comprehensive clinical perspective.

STSI Genomic Collaborations

Pacific Biosciences	Next Gen Sequencing
Life Technologies	Sample Prep for Sequencing
Prognosys Biosciences	Sequencing Tumor
Complete Genomics	Next Gen Sequencing
Illumina	Bioinformatics
Raindance	Sample Prep for Sequencing
Regulus	miRNA for CV therapeutics
Alnylam	siRNA for therapeutics
Gen-Probe	Fusion genes in cancer
Agilent	Sample prep for sequencing
GeneGo	Gene ontogeny/pathways

Clinical Research Collaborations

Sanofi-Aventis	Individualized Medicine
Qualcomm	Wireless Medicine
The Medicines Company	Anti-platelet clinical trial
Navigenics, Microsoft, Affymetrix	Clinical assessment of genome scans
HUYA Biosciences	Atrial fibrillation drug
Portola Pharmaceuticals	Anti-platelet clinical trial using genotyping
Medtronic	Prediction of ICD Need
CardioDx	Prediction of Vulnerable Plaque
Johnson and Johnson	Individualized Medicine
Accumetrics	Clinical trial of individualized dosing
WebMD	Educating physicians on genomic medicine

Cross-CTSA Collaborations