Facilities Tour
Scripps Translational Science Institute
Scripps Translational Science Institute is strategically headquartered at 3344 North Torrey Pines Court off of North Torrey Pines Road, La Jolla, CA 92037. Our offices occupy 14,500 square feet. The building is adjacent to Torrey Pines drive in the heart of the La Jolla and San Diego bio-tech research community and neighboring facilities the at both The Scripps Research Institute and Scripps Health. This location is in close proximity to the area’s largest concentration of basic science, high technology and clinical science academic institutes, research facilities, and health care institutions.
Scripps Health Clinical Research Center
The Scripps Clinical Research Center is located at 11025 North Torrey Pines Road, San Diego, CA 92037. The facility is less than 1 mile from the Scripps Translational Science Institute and 1 block from Scripps Green Hospital and the Anderson Outpatient Facility. The facility is 34,387 square feet and is located within the hub of San Diego’s biotech and research region, which contains Scripps Clinic/Scripps Green Hospital, The Scripps Research Institute, The Scripps Translation Science Institute, the La Jolla Allergy and Immunology Institute, the Burnham Institute, and the Neuroscience Institute along with multiple major pharmaceutical and biotech research/development centers. The facility serves as home base to 115 of our 140 research assigned staff and The Scripps Research Institute’s Normal Blood Donor Program. Additionally, the Scripps Clinical Research Center facility houses all the Scripps Health IRB and senior administrative staff. The facility offers 11 research visit/exam rooms with a blood and specimen collection and processing unit, up to 12-hour research infusion capabilities, and investigator stations. Labs include 2 fume hoods, 1 tissue culture rooms, and high quality benching. It has dedicated training areas for group sessions as small as 2-3 upwards to 100 in a fully technologically integrated environment.
The Scripps Clinical Research Center houses the Scripps Health Division of Clinical Research Services (CRS). The CRS is the core provider of Scripps’ resources for participant and clinical interactions. CRS seeks opportunities to collaborate with the over 550 local pharmaceutical development companies within a twenty-mile radius of Scripps bringing novel therapeutic, diagnostic, bio-technical, and medical devices into its portfolio of studies. CRS capitalizes on this tremendous resource of innovation and collaboration in Scripps’ backyard to benefit San Diego and its environs by managing and/or overseeing all aspects of clinical research conducted in Scripps facilities and programs. As Scripps revitalizes its proud 83-year medical research and education heritage, these opportunities are fully available to the Scripps Translational Science Institute (STSI) with the explicit goal of taking translational medical research to a new level of excellence through intra- and inter-institutional collaborations.
Main Objectives
- Integrate and streamline the participant and clinical support components of STSI translational/clinical research that drive progress in individualized medicine.
- Maximize the testing of new drugs and technologies by taking advantage of Scripps’ diverse subject population and variety of health care delivery methods.
- Promote a culture of compliance by modeling ethical behavior and teaching Good Clinical Practice and scientific integrity that pervades all areas of STSI research.Support the training and continuing education of translational/clinical investigators and research workers with an innovative and cohesive education program.
The CRS infrastructure is a streamlined clinical trials support system enhancing our investigation into new drug and treatment modalities and also existing drugs for new indications or in new combinations to combat human diseases. As more resources are marshaled and new therapeutic agents are discovered, CRS will gain “omic” momentum as it links STSI colleagues in the medical community with trials. Such trials will be carried out in collaboration with our local practice groups through out the Scripps system as need and interest escalates.
CRS supports studies through its dedicated centralized program for core research support functions. The inpatient research function is a “scatter-bed” model, allowing all five hospitals to be engaged as community needs warrant. The outpatient or ambulatory based research occurs in multiple clinical settings but primarily within the facilities and divisions of Scripps Clinic. Research subjects are integrated into the routine daily census or service/practice settings in order to “normalize” as much as possible research tasks into day-to-day operations. Currently we support over 800 active clinical research protocols with over 90,000 subjects, and crossing broad interdisciplinary disease categories holding great expectation and promise for “omic” research.
CRS serves all clinical investigations irrespective of phase of clinical trial or size of study insuring conduct of the protocol is always under Good Clinical Practice (GCP) guidelines as described below. We supports protocol development and design, staffing, staging, business and legal aspects, patient recruiting, protocol compliance, data and safety monitoring, data collection, data analysis and report/presentation Any Scripps researcher can avail themselves of our support services. Programs that will use the overarching coordination and management effort of CRS include the Scripps Individualized Medicine Advanced Clinical Trials (SIMACT), community based research in diabetes from the Scripps Whittier Institute, pediatric research in outcomes at Rady Children’s Hospital, epidemiology, pharmacy and nursing research from San Diego State University.
CRS actively identifies clinical investigators within Scripps and facilitates their participating in investigator initiated and multi-center, cooperative group clinical trials. Regardless of a study’s sponsorship, whether by industry, tax-exempt, or governmental programs, CRS develops research subject recruitment strategies and programs, directs the compilation, maintenance and reporting of research, provides training activities in research compliance, and supports dissemination of research within and without Scripps. CRS insures scientific content, accuracy of reports, web site and other communications for the annual or other periodicity reporting requirement by funding agencies, research sponsors, and Scripps corporate needs.
CRS provides a standardized, and centralized system process this is available throughout the enterprise. The CRS system process provides preliminary scientific, administrative and regulatory services and training to researchers interested in pursuing research. Once a research project has been developed, the CRS system process provides an enterprise wide and web based electronic research system that supports the application, review, conducting, and oversight of research protocols. The system process provides scientific review, administrative review, and regulatory review of the protocol. Additionally, this system process provides on-going study management capabilities, including electronic case report forms, scheduling, and milestone tracking. The system process facilitates and integrates with the continuing oversight of research protocols. This continuing oversight provides data that allows for on-going regulatory, compliance and quality assessments. These assessments allow for on-going protocol evaluation, feedback and CRS self-evaluation
CRS provides centralized and comprehensive infrastructure that supports CRS system process and other clinical research activities through out the enterprise These functional service areas cover seven key functional areas: administration, grants, regulatory and compliance, research informatics, bio statistics, operations and staff support, and support services.
